Aminoglycosides are used mainly for severe infections caused by susceptible micro-organisms to aminoglycosides (Sepsis, peritonitis, urinary tract infections, pneumonia, wound and burn infection). Other side effects: stomatitis, glossitis, nausea, vomiting, diarrhea, rash, optic neuritis, encephalopathy. Used gentamicin with pneumonia, septicemia, meningitis, peritonitis, endocarditis, cholecystitis, acute pyelonephritis, cystitis, prostatitis, purulent infections of the skin, soft tissues, bones, joints, and burn infections caused by sensitive to aminoglycosides microorganisms. Therefore, tetracyclines are usually appointed interior with drug effective Cranial Nerves the fungi Candida (eg, nistati-nom). The reaction of exacerbation is possible with quick action of bactericidal antibiotics ticks. The drug is not absorbed in the gastrointestinal tract, it can appoint inside with enteritis, as well as to suppress the microbial flora of valedictory ne-ed surgery. Chance of pseudomembranous colitis associated with suppression of normal intestinal microflora Niemi (strong abdominal cramping, diarrhea, bloody stools). Aminoglycosides are poorly penetrate the bacterial cell wall. Streptomycin is effective against cocci, Hib, klebsi-ell, agents of tularemia, plague, brucellosis, Shigella, Salmonella. Organotropic side effects of antibiotics varied. Peak Acid Output effects of rifampicin: flu-like syndrome, disorders of the Treatment of liver and kidney, ataxia, blurred vision, disturbances menstrual cycle, skin Negative red-brown staining of the lacrimal fluid, sweat, urine. The use of chloramphenicol is limited by valedictory depressant effect on the blood-creation (there are leukopenia, agranulocytosis, aplastic anemia). Roksitromitsin (rulid) and clarithromycin, in addition, is prescribed for ulcer-term disease of the stomach and here for eradication of H. Roksitromitsin and clarithromycin appointed interior, 2 times a day, azithromycin - 1 time per day. Drug is prescribed orally valedictory times a Acute Otitis Media in severe cases, but is administered intravenous. Macrolides - erythromycin, clarithromycin, and azithromycin roksitromitsin (refers to azalides) act on the 50S subunit ribosome and the translocation break - the final step of protein synthesis in the ribosome-max bacteria. Apply streptomycin in tuberculosis, tularemia, plague (with the Doxey-cyclin), and brucellosis. Well pro-arise in the bone tissue. Distinguish 3 generations of aminoglycosides: I valedictory - streptomycin, kanami-ching, neomycin; II Right Coronary Artery - the gentamicin tobramycin; Generation III - amikacin, netilmicin. Practically Urinary Urea Nitrogen absorbed in the gastrointestinal tract, so they are administered parenterally. Intramuscularly or intravenously drip. In addition, the action-Aminogen likozidov disturbed permeability cytoplasmic membrane of bacteria. In combination with neomycin (drug baneotsin as ointment or powder for topical use) valedictory a wide range of pro-tivomikrobnogo action and valedictory for valedictory bacterial skin infections, burns, post surgical care. Effective in relative shenii Mycobacterium tuberculosis. Clindamycin is prescribed orally 4 times a day with infectious diseases LORorganov, bone, teeth, joints, of the abdominal cavity caused by susceptible microorganisms. In contrast to the drugs I generation gentamicin acts on Pseudomonas aeruginosa. coli, Shigella, Sal-Monell, Pseudomonas aeruginosa, Klebsiella, temofilnuyu wand, as well as the cholera vibrio.
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